Table 1.
Clinical and laboratory data of leprosy patients before, during, and 5 years after MDT
| Nº | ID | Age† | Sex | Race | BI-b | APGL-1-b‡,* | HP | MDT–MB/PB (doses) | RE | NE | BI-a | APGL-1-a‡,* |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MB1 | LCN | 55 | M | CAU | 5+ | 13.5 | LL | MB (24) | EN | – | 1+ | 1.6 |
| MB2 | LSS | 50 | F | CAU | 3+ | 1.8 | BL | MB (12) | RR | Yes | Neg | 0.3 |
| MB3 | JSA | 33 | M | CAU | 4+ | 1.5 | BL | MB (12) | – | – | Neg | 0.1 |
| MB4 | CAL | 39 | F | CAU | 4+ | 2.2 | LL | MB (24) | – | – | Neg | 0.5 |
| MB5 | AAR | 38 | M | CAU | 4+ | 4.8 | LL | MB (24) | EN | – | Neg | 0.9 |
| MB6 | CAL | 39 | F | CAU | 5+ | 5.5 | LL | MB (12) | – | Yes | Neg | 1.0 |
| MB7 | DCS | 51 | M | CAU | 3+ | 2.6 | LL | MB (24) | – | Yes | Neg | 0.4 |
| MB8 | RI | 69 | M | CAU | 3+ | 4.4 | BL | MB (24) | RR | Yes | Neg | 0.4 |
| MB9 | lARV | 53 | M | CAU | 3+ | 6.5 | BL | MB (12) | EN | – | Neg | 0.5 |
| MB10 | APS | 43 | M | BLA | 1+ | 1.1 | BL | MB (4) | – | – | NP | NP |
| MB11 | MLJ | 45 | F | BLA | 3+ | 4.2 | LL | MB (24) | EN | – | 2+ | 4.1 |
| PB1 | RDM | 43 | M | CAU | Neg | 0.6 | TT | PB (6) | – | – | Neg | 0.3 |
| PB2 | SLS | 35 | M | CAU | Neg | 0.3 | BT | PB (6) | – | Yes | Neg | 0.3 |
| PB3 | JES | 44 | M | CAU | Neg | 0 | BT | PB (6) | – | – | Neg | 0 |
| PB4 | CMO | 61 | F | CAU | Neg | 0.3 | TT | PB (6) | – | – | Neg | 0.3 |
| PB5 | SR | 51 | M | CAU | Neg | 0.7 | TT | PB (6) | – | – | Neg | 0.2 |
| PB6 | JPS | 42 | F | CAU | Neg | 0.5 | BT | MB (12) | RR | – | Neg | 1.1 |
| PB7 | AFAS | 21 | M | CAU | Neg | 0.9 | BT | MB (12) | RR | – | Neg | 0.8 |
| PB8 | MBSA | 58 | F | BLA | Neg | 1.5 | BT | PB (6) | – | – | Neg | 0.8 |
Notes:
†
Expressed as years;
‡
expressed as pg/mL;
*
cut-off: 1.0/positive result: ≥1.0.
Abbreviations: MDT, multidrug therapy; Nº, number; ID, identification; BI-b, bacterial index before MDT; APGL-1-b, anti-PGL-1 before MDT; HP, histopathologic classification; MB, multibacillary; PB, paucibacillary; RE, reactional episodes; NE, neuritis; BI-a, bacterial index after MDT; APGL-1-a, anti-PGL-1 after MDT; M, male; F, female; CAU, caucasian; BLA, black; Neg, negative; LL, lepromatous; BL, borderline-lepromatous; TT, tuberculoid; BT, borderline-tuberculoid; EN, erythema nodosum; RR, reverse reaction; NP, not performed.