Table 2.

Doses of fluticasone (μg/day) at which 80% and 90% of the maximum effect is achieved, as derived from a negative exponential model^*

Outcome measure	80% of maximum effect achieved	90% of maximum effect achieved
FEV1	146	209
Morning PEF	172	247
Evening PEF	175	251
Use of rescue medication	71	102
Major exacerbations	108	155
Night awakenings	135	193

^*The effect obtained with 1000 μg/day of fluticasone was considered to be the “maximum effect” for the purposes of this analysis. 

FEV₁=forced expiratory volume in one second; PEF=peak expiratory flow.