Table 1.
Patient and tumor characteristics of 108 patients with newly diagnosed glioblastoma
| Characteristics | n | Percent |
|---|---|---|
| Total cases | 108 | |
| Age | ||
| Median | 65 | |
| Range | 18–92 | |
| Gender | ||
| Female | 39 | 36.1 |
| Male | 69 | 63.9 |
| Karnofsky Performance Status | ||
| 80–100 (normal activity) | 80 | 74.1 |
| 50–70 (requires assistance) | 24 | 22.2 |
| ≤40 (disabled) | 4 | 3.7 |
| Extent of Resection | ||
| Biopsy | 24 | 22.6 |
| Partial resection | 25 | 23.6 |
| Near gross-total resection | 18 | 1.7 |
| Gross-total resection | 39 | 36.8 |
| EGFR Expression | ||
| Normal | 34 | 37.4 |
| Abnormal | 57 | 62.6 |
| MGMT Immunohistochemical Expression | ||
| ≥20% | 40 | 37.0 |
| <20% | 68 | 63.0 |
| PTEN Expression | ||
| Loss | 58 | 56.9 |
| Retained | 44 | 43.1 |
| Standard Treatment* | ||
| Yes | 72 | 79.1 |
| No | 19 | 20.9 |
| Radiation | ||
| Yes | 98 | 90.7 |
| No | 10 | 9.3 |
*Standard treatment = Temozolomide and radiation.
EGFR (PTEN) expression data available in 91 (102) patients.