Table 4.

β Coefficients and ORs for refitted Apfel and Sinclair models

	Original β coefficient	New β coefficient	p Value	Odds ratio estimate	95% CI
Apfel model
Intercept	−2.28	−3.48	<0.0001
Female sex	1.27	1.19	<0.0001	3.279	1.972 to 5.452
History of PONV or motion sickness	0.65	0.90	<0.0001	2.471	1.937 to 3.153
Non-smoker	0.72	0.14	0.49	1.155	0.767 to 1.739
Postoperative opioid use	0.78	0.13	<0.0001	2.351	1.806 to 3.061
Sinclair model
Intercept	−5.97	−2.41	<0.0001
Male sex	−1.03	−0.70	0.01	0.498	0.735 to 0.894
History of PONV	1.14	0.98	<0.0001	2.652	2.039 to 3.449
Smoker	−0.42	−0.12	0.58	0.888	0.585 to 1.348
Age	−0.14	−0.21	<0.0001	0.811	0.735 to 0.894
Duration of surgery	0.46	0.30	<0.0001	1.355	1.192 to 1.541
Primary anesthesia=GA	2.36	1.22	<0.0001	3.388	2.232 to 5.143
Breast plastics	1.90	−0.20	0.46	0.818	0.481 to 1.393
Gyn surgery, but not D&C	1.20	0.07	0.64	1.070	0.808 to 1.416

GA, general anesthesia; gyn, gynecological; IM, intramuscular; PONV, postoperative nausea and vomiting.