Table 5.
Summary of results (SK enriched group)
| No. | Donor | Treatment | Lytic Dist | Pre-Wt. | Post Wt. | (%) | R.M.S. | Channels | (min) | Mobilized | Fragmented |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |
AH |
Control |
2.1 cm |
0.258 |
0.254 |
2 |
+1 |
No |
- |
No |
No |
| 2 |
AH |
Vibrate |
2.0 cm |
0.297 |
0.184 |
38 |
+5 |
Yes |
10 |
No |
No |
| 3 |
HG |
Vibrate |
2.0 cm |
0.295 |
0.177 |
40 |
+5 |
Yes |
10 |
No |
No |
| 4 |
HG |
Control |
2.1 cm |
0.288 |
0.280 |
3 |
+1 |
No |
- |
No |
No |
| 5 |
AH |
Vibrate |
1.5 cm |
0.371 |
0.206 |
44 |
+6 |
Yes |
10 |
No |
No |
| 6 |
AH |
Vibrate |
2.5 cm |
0.255 |
0.126 |
51 |
+41 |
Yes |
5 |
No |
No |
| 72 |
HG |
Vibrate |
1.5 cm |
0.352 |
0.161 |
54 |
+5 |
Yes |
10 |
No |
No |
| 8 |
HG |
Control |
2.3 cm |
0.262 |
0.246 |
6 |
+03 |
No |
- |
No |
No |
| 9 |
AH |
Vibrate |
2.5 cm |
0.236 |
0.061 |
74 |
+6 |
Yes |
5 |
Yes |
No |
| 10 |
AH |
Control |
1.5 cm |
0.453 |
0.436 |
4 |
+1 |
No |
- |
No |
No |
| 11 |
HG |
Vibrate |
1.8 cm |
0.303 |
0.125 |
59 |
+5 |
Yes |
5 |
No |
No |
| 12 |
AH |
Control |
2.1 cm |
0.286 |
0.280 |
2 |
+1 |
No |
- |
No |
No |
| 13 |
HG |
Control |
1.9 cm |
0.299 |
0.290 |
3 |
+1 |
No |
- |
No |
No |
| 14 |
HG |
Control |
1.6 cm |
0.341 |
0.338 |
1 |
+1 |
No |
- |
No |
No |
| 15 |
AH |
Vibrate |
2.3 cm |
0.255 |
0.133 |
48 |
+5 |
Yes |
5 |
No |
No |
| 16 | HG | Control | 2.3 cm | 0.259 | 0.251 | 3 | +1 | No | - | No | No |
Results of; initial lytic to clot separation distance (cm), Percent Clot Dissolution (%), Relative Mixing Score (+0 - +7), clot length fluid channel development (Yes or No), time to first observation of clot length fluid channels (min), clot mobilization (Yes or No) and clot fragmentation (Yes vs. No), in view of a 20 minute exposure of remotely administered SK in conjunction with “diastolic” timed LFVP (Vibrate) vs. no LFVP (Control). Donors, AH = Andrew Hoffmann (male), HG=Harjit Gill (female).
1Diminished mixing score in this sample was likely attributed to the relatively small initial clot size (with a leading edge ~2.5 cm from SK).
2This sample run developed a significant leak between the connecting line and blue tip connector of the catheter segment which could not be corrected. Only about 10 minutes of effective LFVP therapy was administered. Mixing score was based on maximum observed prior to the leak.
3Relatively low mixing score in this sample may have also been attributed to a relatively small clot size (with leading edge 2.3 cm from SK).