Table 6.
Risk of death from influenza A/H1N1 in relation to the different polymorphisms studied
| Gen/allele | p | OR (CI 95%) | OR allelic (CI 95%) |
|---|---|---|---|
|
CCL1 rs2282691 |
|
|
1.63 (0.63-4.40) |
| AT |
0.40 |
0.4 (0.07-2.79) |
|
| AA |
0.90 |
1.1 (0.22-5.31) |
|
|
IL1B rs16944 |
|
|
1.55 (0.56-4.50) |
| GG |
0.70 |
1.6 (0.17-14.40) |
|
| AG |
0.30 |
2.8 (0.35-23.02) |
|
|
IL8 rs4073 |
|
|
1.41 (0.53-3.78) |
| TT |
0.70 |
0.7 (0.07-6.11) |
|
| AT |
0.40 |
1.7 (0.51-5.76) |
|
|
IL6 rs1818879 |
|
|
0.96 (0.40-2.28) |
| AG |
0.30 |
0.5 (0.15-1.70) |
|
| AA |
0.50 |
0.5 (0.10-2.76) |
|
|
LTA rs909253 |
|
|
0.46 (0.16-1.27) |
| GG |
0.50 |
0.5 (0.05-4.27) |
|
| AG |
0.06 |
3.1 (0.93-10.53) |
|
|
TNF |
|
|
|
| rs1800750 |
|
|
1.21 (0.55-2.61) |
| AG |
0.30 |
3.5 (0.39-31.76) |
|
| AA |
0.20 |
2.9 (0.58-14.51) |
|
| rs1800629 |
|
|
2.39 (0.51-11.03) |
| AG |
0.30 |
2.5 (0.51-12.26) |
|
| rs361525 |
|
|
0.95 (0.21-4.16) |
| AG |
1.00 |
|
|
| AA | 0.40 | 2.8 (0.31-24.74) |
OR: odds ratio; CI: confidence intervals; allelic OR: comparison with ancestral gene. Results were considered statistically significant when P was <0.05.