Table 2.
Comparison of CPT1A P479L homozygosity in unexpected infant death cases (SIDS, SUDI and infection) occurring in Nunavut (July 1, 1999-June 30, 2011) to the estimated population P479L homozygosity [24], by region and territory
| |
Cases |
Population |
Odds Ratio |
(95%CI) |
2 sided
FETp |
||||
|---|---|---|---|---|---|---|---|---|---|
| n | f | (95%CI) | n | f | (95%CI) | ||||
|
NUNAVUT |
30 |
85.7 |
(69.7-95.2) |
442 |
63.6 |
(59.9-67.2)* |
3.43 |
(1.30-11.47) |
0.006 |
| Qikiqtani |
8 |
88.9 |
(51.8-99.7) |
162 |
53.6 |
(47.8-59.4)* |
6.91 |
(0.90- 308.87) |
0.044 |
| Kivalliq |
16 |
88.9 |
(62.5-98.6) |
170 |
70.0 |
(63.8-75.7) |
3.44 |
(0.77-31.45) |
0.108 |
| Kitikmeot |
6 |
75.0 |
(34.9-96.8) |
110 |
73.3 |
(65.5-80.2) |
1.09 |
(0.19-11.47) |
1.000 |
| Kivalliq & Kitikmeot (combined) | 22 | 84.6 | (65.1-95.6) | 290 | 71.2 | (66.5-75.7) | 2.22 | (0.73-9.04) | 0.178 |
* Genotype frequencies deviated from Hardy-Weinberg equilibrium (p<0.05) [24].
f = frequency. CI = confidence interval. FET = fisher’s exact test.