Table 5.
Type III mean squares and association between CP, ACR, and MCP-1
| Dependent | Model | Predictor | Estimate | StdErr | P-value |
|---|---|---|---|---|---|
| CAC |
ACR + all covariates in the adjusted model |
Log(ACR+1) |
1.5E-01 |
6.6E-02 |
0.02 |
| eGFR + all covariates in the adjusted model |
eGFR |
1.7E-04 |
4.3E-03 |
0.96 |
|
| ACR and MCP-1 + all covariates in the adjusted model |
Log(ACR+1) |
1.5E-01 |
6.6E-02 |
0.02 |
|
| MCP-1 |
-1.7E-04 |
1.1E-03 |
0.87 |
||
| eGFR and MCP-1+ all covariates in the adjusted model |
eGFR |
2.0E-04 |
4.4E-03 |
0.96 |
|
| MCP-1 |
6.0E-05 |
1.1E-03 |
0.95 |
||
| ACR, eGFR and MCP-1+ all covariates in the adjusted model |
eGFR |
6.9E-04 |
4.4E-03 |
0.87 |
|
| Log(ACR+1) |
1.5E-01 |
6.6E-02 |
0.02 |
||
| MCP-1 |
-1.4E-04 |
1.1E-03 |
0.89 |
||
| CarCP |
ACR + all covariates in the adjusted model |
Log(ACR+1) |
1.1E-01 |
5.1E-02 |
0.02 |
| eGFR + all covariates in the adjusted model |
eGFR |
-4.3E-03 |
3.4E-03 |
0.20 |
|
| ACR and MCP-1 + all covariates in the adjusted model |
Log(ACR+1) |
1.1E-01 |
5.2E-02 |
0.02 |
|
| MCP-1 |
3.3E-05 |
8.5E-04 |
0.96 |
||
| eGFR and MCP-1+ all covariates in the adjusted model |
eGFR |
-4.2E-03 |
3.4E-03 |
0.21 |
|
| MCP-1 |
5.7E-05 |
8.6E-04 |
0.94 |
||
| ACR, eGFR and MCP-1+ all covariates in the adjusted model |
eGFR |
-3.9E-03 |
3.4E-03 |
0.25 |
|
| Log(ACR+1) |
1.1E-01 |
5.2E-02 |
0.03 |
||
| MCP-1 |
-1.1E-04 |
8.6E-04 |
0.90 |
||
| AorCP | ACR + all covariates in the adjusted model |
Log(ACR+1) |
1.9E-01 |
6.9E-02 |
0.005 |
| eGFR + all covariates in the adjusted model |
eGFR |
-5.2E-03 |
4.4E-03 |
0.24 |
|
| ACR and MCP-1 + all covariates in the adjusted model |
Log(ACR+1) |
1.9E-01 |
6.9E-02 |
0.006 |
|
| MCP-1 |
6.4E-04 |
1.1E-03 |
0.56 |
||
| eGFR and MCP-1+ all covariates in the adjusted model |
eGFR |
-4.8E-03 |
4.5E-03 |
0.28 |
|
| MCP-1 |
7.7E-04 |
1.1E-03 |
0.49 |
||
| ACR, eGFR and MCP-1+ all covariates in the adjusted model | eGFR |
-4.2E-03 |
4.5E-03 |
0.34 |
|
| Log(ACR+1) |
1.9E-01 |
6.9E-02 |
0.007 |
||
| MCP-1 | 4.9E-04 | 1.1E-03 | 0.66 |
CP, calcified plaque; ACR, albumin: creatinine ratio; eGFR, estimated glomerular filtration rate; MCP-1, monocyte chemoattractant protein-1; CAC, coronary artery calcified plaque; CarCP, carotid artery calcified plaque; AorCP, infrarenal aorta calcified plaque.
The covariates included in the adjusted model are age, sex, smoking, HbA1c, BMI, and LDL.