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. 2012 Dec 2;1:61. doi: 10.1186/2046-4053-1-61

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Copyright ©2012 Griebeler et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Example of network of direct comparisons for the multiple-treatments meta-analysis for the outcome of interest that will be used. The thickness of the connecting lines is proportional to the number of available direct comparisons. The size of each node is proportional to the number of trials that investigated each treatment. The information in this figure is preliminary and will be updated after the search and analysis. AC = anticonvulsant; ARI = aldose reductase inhibitor; SSRI = selective serotonin reuptake inhibitor.