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. 2013 Jan 2;8(1):e53270. doi: 10.1371/journal.pone.0053270

Figure 3. Chromatin organization at genomic region around Whey Acidic Protein gene (Wap).

Figure 3

Summary of markers of chromatin organization aligned to the Wap region in mouse genome assembly mm9 in the UCSC Genome Browser. (A–B) ChIP-seq reads for H3K4me2 in liver tissue (Liver, red), lactating mammary gland (Lactating MG, blue) and mammary epithelial cells isolated from 12 week virgin mammary glands (Virgin MEC, black). ECR: genomic locations of DHS conserved in mouse and rabbit [17], [54], CpG island is indicated by dark green bar. (B) Close-up of Wap region from (A). H3Ac: Summary of H3Ac-ChIP results for Wap promoter and HSS2 (see also Fig. S3) in lactating mammary gland (Lact, blue) and Liver tissue (liver, red): closed rectangle indicates enrichment of H3Ac at site, open rectangle indicates lack of enrichment at site. DHS: Summary of DHS results for rabbit from [17], [54]. Closed rectangle indicates presence of DHS, open rectangle indicates absence of DHS.