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. 2013 Jan 2;8(1):e53236. doi: 10.1371/journal.pone.0053236

Table 1. Characteristics of patients by severe AKI status.

Severe AKI (n = 66) No severe AKI (n = 46) P value
Demographic characteristics
Age (yr) 44 (33–56) 34 (24–45) 0.002
Male sex 57 (86%) 41 (89%) 0.663
Hematological markers
Admission platelet count (×109/L) 24 (11–31) 51 (36–73) <0.0001
Nadir platelet count (×109/L) 14 (9–25) 45 (34–68) <0.0001
Admission leukocyte count (×109/L) 17.9 (11.5–25.1) 11.5 (8.0–15.9) 0.001
Peak leukocyte count (×109/L) 21.3 (15.3–31.4) 15.5 (10.4–21.2) 0.0001
Nadir hematocrit (%) 29.5 (24.4–32.8) 36.9 (35.0–38.9) <0.0001
Renal function
Peak blood urea nitrogen (mmol/L) 30.2 (25.9–35.4) 11.3 (7.6–16.1) <0.0001
Peak serum creatinine (µmol/L) 729 (539–956) 181 (132–240) <0.0001
Peak uric acid (µmol/L) 511 (392–630) 549 (467–659) 0.185
Clinical records
Shock 16 (24%) 4 (9%) 0.035
Proteinuria 60 (91%) 41 (89%) 0.758
Hematuria 47 (71%) 10 (22%) <0.0001
Dialysis required 57 (86%) 0 (0%) <0.0001
Length of hospital stay (days) 21 (14–29) 9 (7–11) <0.0001

Data are median (IQR) or number (%).