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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Exp Neurol. 2012 Oct 8;239:102–110. doi: 10.1016/j.expneurol.2012.10.002

Figure 4. Plasma cholesterol profile at 24 weeks of age.

Figure 4

Fasting plasma samples were pooled for each group and fractionated by FPLC. Total cholesterol was measured in each fraction. In A, the concentration of cholesterol plotted against the fraction number **p<0.01, ***p<0.001 entire curve vs. ApoE−/− db/db; ϕ p<0.05 entire curve vs. ApoE wt db/+. In B, the proportion of cholesterol distributed to each lipoprotein fraction is expressed for each mouse genotype. *p<0.05, **p<0.01, ***p<0.001 VLDL vs. ApoE−/− db/db; ♦♦p<0.05, ♦♦♦p<0.001 LDL vs. ApoE−/− db/db; ϕ p<0.05 LDL vs. ApoE−/−/ApoB100only/ob/ob.