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. Author manuscript; available in PMC: 2014 Jan 9.
Published in final edited form as: J Mol Biol. 2012 Oct 16;425(1):41–53. doi: 10.1016/j.jmb.2012.10.009

Figure 3. Impact of HIV-1 RT mutants on viral fitness.

Figure 3

Each of the 10 RT mutants, and a wt control, was passaged with a wt reference strain in a head-to-head competition assay. Mutants are assembled by RT position, and respective fitness differences (WD) are displayed on a log-scale. Asterisk symbols denote level of significance with numerical values along horizontal line showing fold difference from wt. Error bars represent SEM, standard error of the mean. * P value < 0.05; ** P value < 0.01; *** P value < 0.001.