. Author manuscript; available in PMC: 2013 Dec 1.

Published in final edited form as: Psychol Aging. 2012 Sep 3;27(4):1008–1017. doi: 10.1037/a0029857

Table 3.

Estimated Paths of Global Cognitive Change in Alzheimer's Disease Subgroups with Different Durations of Follow-up^*

			Alzheimer's Disease Subgroups
Effects	Model Term	Model Output	≥ 6 Visits (n = 210)	≥ 7 Visits (n = 192)	≥ 8 Visits (n = 170)	≥ 9 Visits (n = 143)
Fixed	Intercept	Estimate	-0.933^*	-0.925^*	-0.915^*	-0.908^*
		95% CI	-0.996,-0.871	-0.993, -0.861	-0.984, -0.841	-0.993, -0.827
	Slope 1	Estimate	0.004	0.004	0.006	0.004
		95% CI	-0.013, 0.022	-0.011, 0.022	-0.007, 0.023	-0.009, 0.020
	Slope 2	Estimate	-0.088^*	-0.089^*	-0.087^*	-0.094^*
		95% CI	-0.102, -0.075	-0.101, -0.076	-0.101, -0.074	-0.110, -0.078
	Slope 3	Estimate	-0.377^*	-0.373^*	-0.377^*	-0.403^*
		95% CI	-0.417, -0.340	-0.416, -0.335	-0.423, -0335	-0.460, -0.350
	Ch. point 1	Estimate	-7.473^*	-7.469^*	-7.519^*	-7.226^*
		95% CI	-8.365, -6.757	-8.151, -6.750	-8.418, -6.882	-8.081, -6.561
	Ch. point 2	Estimate	-1.864^*	-1.850^*	-1.850^*	-1.666^*
		95% CI	-2.144, -1.584	-2.190, -1.600	-2.204, -1.565	-2.017, -1.391
Random	Intercept	Estimate	0.190^*	0.196^*	0.208^*	0.214^*
		95% CI	0.153, 0.236	0.155, 0.246	0.168, 0.262	0.165. 0.281
	Slope 1	Estimate	0.0004^*	0.0004^*	0.0004^*	0.0004^*
		95% CI	0.0002, 0.0009	0.0002, 0.0009	0.0002, 0.0009	0.0002, 0.0009
	Slope 2	Estimate	0.001^*	0.001^*	0.001^*	0.001^*
		95% CI	0.001, 0.002	0.001, 0.002	0.001, 0.002	0.001, 0.003
	Slope 3	Estimate	0.042^*	0.043^*	0.047^*	0.060^*
		95% CI	0.030, 0.059	0.030, 0.062	0.032, 0.068	0.041, 0.090
	Ch. point 1	Estimate	0.027^*	0.022^*	0.028^*	0.025^*
		95% CI	0.001, 0.889	0.001, 0.788	0.001, 0.968	0.001, 0.740
	Ch. point 2	Estimate	0.115^*	0.138^*	0.182^*	0.166^*
		95% CI	0.015, 0.316	0.003, 0.378	0.002, 0.538	0.002, 0.597
	Error	Estimate	0.085^*	0.082^*	0.081^*	0.077^*
		95% CI	0.079, 0.092	0.075, 0.088	0.075, 0.088	0.071, 0.084

Note. Results were estimated from 5 separate mixed-effects change point models. Fixed effects indicate the estimated group mean and random effects indicate person specific deviation from the group mean. CI, confidence interval.

p <0.05