Table 4.
Biologically active compounds isolated from medicinal plants of Laos.
|
Gongronema napalense (Wall.) Decne (Asclepiadaceae) (SLA7530) (Vine) (Libman et al., 2008)
| |||||||
|---|---|---|---|---|---|---|---|
| Sample code | Chemical name of compound | Chemical structure of compound | Bioactivity of sample: ED50/IC50 (ng/mL)
|
||||
| KB
|
D6
|
W2
|
|||||
| ED50 | IC50 | SI | IC50 | SI | |||
| SLA7530-K001 | Gongroneside A |
|
>20000 | 2330 | >8.5 | 2020 | >13.7 |
| Diospyros quaesita Thw. (Ebenaceae) (SLA7062) (LF+ST) (Ma et al., 2008) | |||||||
| SLA7062-K001 | Betulinic acid 3β-caffeate |
|
2500 | 870 | 2.9 | 607 | 4.1 |
| SLA7062-K001a | Betulinic acid |
|
>40000 | 3696 | >10.8 | 3776 | >10.5 |
| SLA7062-K001b | Betulinic acid 3β-bisacetylcaffeate |
|
2070 | 480 | 4.3 | 443 | 4.7 |
| SLA7062-K004 | Pinoresinol |
|
>40000 | 1361 | >29.3 | 3150 | >12.6 |
| Nauclea orientalis (L.) L. (Rubiaceae) (SLA7018) (TW) (He et al., 2005) | |||||||
| SLA7018-K002 | epi-Methoxy-naucleaorine |
|
>20000 | 6535 ± 151 | >3.1 | 6979 ± 8 | >2.9 |
| SLA7018-K003 | Oleanolic acid |
|
21000 | 2116 ± 308 | 9.9 | 2335 ± 13 | 9.0 |
| SLA7018-K006 | Naucleaorine |
|
20000 | 3610 ± 595 | 5.5 | 4192 ± 8 | 4.8 |
| SLA7018-K008 | 3α,23-Dihydroxy-urs-12-en-28-oic acid |
|
>20000 | 4567 ± 702 | >4.4 | 6006 ± 2581 | >3.3 |
| Rourea minor Leenh. (Connaraceae) (SLA7006) (Vine) (He et al., 2006) | |||||||
| SLA7006-K005 | Rouremin |
|
>20000 | 4000 | >5 | 3500 | >5 |
| SLA7006-K008 | Rourinoside |
|
>20000 | 2100 | >9 | 1200 | >16 |
|
Asparagus cochinchinensis (Lour.) Merr. (Liliaceae) (SLA7037) (RT) (Zhang et al., 2004)
| ||||||||
|---|---|---|---|---|---|---|---|---|
| Sample code | Chemical name of compound | Chemical structure of compound | Bioactivity of sample: IC50(μg/ml)
|
|||||
| KB | Col-2 | LNCaP | LU-1 | HUVEC | hTERT | |||
| SLA7037-K001 | Asparacosin A |
|
10.7 | >20 | >20 | >20 | >20 | >20 |
| SLA7037-K003 | Asparacoside |
|
4.8 | 5.4 | 10.1 | 4.2 | 4.1 | 4.3 |
| SLA7037-K004 | 3′-Methoxy-asparenydiol |
|
12.0 | >20 | >20 | 19.7 | >20 | 0.3 |
| SLA7037-K006 | 3″-Methoxy-nyasol |
|
9.0 | 6.3 | 6.6 | 4.5 | 6.7 | 1.2 |
| SLA7037-K007 | 3″-Hydroxy-4″-methoxy-4″-dehyroxy-nyasol |
|
9.0 | 11.7 | 11.6 | 7.2 | 16.4 | 0.2 |
| SLA7037-K010 | Asparenydiol |
|
2.4 | >20 | >20 | 19.8 | >20 | 0.2 |