Table 4.

Neutralizing antibody responses of individual ewes in the Phase II Group #4 study. These animals received 1 × 10⁵ PFU s.c. of the arMP-12ΔNSm 21/384 vaccine candidate. All 6 ewes had live fetuses measuring 29 to 32 cm C-R and ewe #63 had twin fetuses.

Phase II Group #4
	arMP-12ΔNSm 21/384 (1 × 105PFU)
Day	#59†	#60	#61	#62	#63	#64
1	<1:10‡	<1:10	<1:10	<1:10	<1:10	<1:10
2	<1:10	<1:10	<1:10	<1:10	<1:10	<1:10
3	<1:10	<1:10	<1:10	<1:10	<1:10	<1:10
4	<1:10	<1:10	<1:10	<1:10	<1:10	<1:10
5	<1:10	<1:10	<1:10	<1:10	<1:10	<1:10
6	<1:10	<1:10	<1:10	<1:10	<1:10	<1:10
7	<1:10	20	20	20	<1:10	<1:10
9	20	160	160	320	320	20
13	80	640	160	1280	320	20
20	80	320	160	5120	1280	20
27	80	1280	160	1280	1280	20
34	80	640	160	1280	1280	20
41	80	1280	320	1280	320	20
48	80	1280	320	1280	1280	20
55	80	320	320	1280	320	20
62	80	320	320	640	320	20

^†Ewe identification number

^‡Data are expressed as the reciprocal of plaque-reduction neutralization 80% antibody titer. Minimum detection limit of the assay is 1:10.