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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Neurobiol Dis. 2012 Oct 12;50:69–75. doi: 10.1016/j.nbd.2012.10.005

Figure 1. Neonatal hyperoxia exposure decreased adult spatial learning and memory.

Figure 1

Time (seconds) taken by the adult mice exposed to Air (line with open green circles), Hypoxia (dashed line with blue squares) and Hyperoxia (dashed line with red triangles) to find the platform in water maze navigation task. Mice exposed to air or hypoxia in the neonatal period performed comparably, but neonatal exposure to hyperoxia impaired the ability of mice to find the submerged platform. means ± SEM; n= 22 in air, 13 in hypoxia, and 16 in hyperoxia.*p<0.05 vs. air-exposed mice RM ANOVA).