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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Neurobiol Dis. 2012 Oct 12;50:69–75. doi: 10.1016/j.nbd.2012.10.005

Figure 2. Neonatal hyperoxia exposure decreased memory, increased exploratory behavior and decreased anxiety in adult mice.

Figure 2

(A) Novel Object Recognition test: Hyperoxia-exposed mice spent less time with novel objects as compared to air-exposed mice. (B) Elevated Plus Maze: Hyperoxia-exposed mice spent more time in the open center and less time in the closed area. (C) Open Field Test: Hyperoxia-exposed mice traveled a greater distance in the center area (D) Rotarod test: No statistical differences were noted in time spent on the rod. Air-exposed: solid green bars, hypoxia-exposed mice: cyan angled stripes, hyperoxia-exposed: red bars with horizontal stripes; means± SEM; n= 10 in air, 7 in hypoxia, and 7 in hyperoxia.*p<0.05 vs. air-exposed mice.