Table 3.

Parameters used to predict the Alexa Fluor 555-PAMAM G3 efflux behavior

Nominal $C_A^I$ [μM]	$C_{A0}^{II}$ [μM]	$C_{Ab}^{II}$ [μM]	Km,uptake [μm/min]	AVrelease [μm−1]	Fraction Remaining	r2
0.4	1.37 ± 0.75	0.87 ± 0.43	0.062 ± 0.039	2.52 ± 0.16	0.64 ± 0.47	0.70
0.6	1.42 ± 0.69	0.89 ± 0.30	0.073 ± 0.057	0.74 ± 0.11	0.62 ± 0.37	0.84
0.9	2.17 ± 0.87	1.62 ± 0.68	0.065 ± 0.063	2.40 ± 0.18	0.75 ± 0.43	0.82
1.1	2.72 ± 1.47	1.86 ± 0.71	0.018 ± 0.013	0.99 ± 0.15	0.68 ± 0.45	0.55

$C_A^I$-bulk concentration; $C_{A0}^{II}$-initial concentration inside cells; $C_{Ab}^{II}$-final concentration inside cells; K_m,uptake -mass transfer coefficient; AV_release-surface area to volume ratio, r²-quality of fit