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Sialyltransferases catalyze the transfer of sialic acid from CMP-sialic acid to a suitable acceptor, commonly a Gal, GalNAc, or Sia terminated glycan or glycoconjugates. The most common sialic acid form, Neu5Ac, is shown as an example. R, glycans or glycoconjugates; R′, Neu5Ac- or Gal-terminated glycans or glycoconjugates.
