Table 1.
Clinical and demographic characteristics of HIV-infected study patients by HCV status (N=764)
| Characteristic | HCV-uninfected N = 604 |
HCV-infected N = 160 |
p-value |
|---|---|---|---|
| N (%) | N (%) | ||
| Sex | |||
| Male | 531 (88) | 133 (83) | |
| Female | 73 (12) | 27 (17) | 0.1 |
| Age (years) | |||
| < 30 | 43 (7) | 5 (3) | |
| 30–39 | 141 (23) | 23 (14) | |
| 40–49 | 261 (43) | 80 (50) | |
| ≥50 | 159 (26) | 52 (33) | 0.01 |
| Race | |||
| White | 399 (66) | 95 (59) | |
| Black | 105 (17) | 37 (23) | |
| Hispanic | 55 (9) | 12 (8) | |
| Other/Unknown | 45 (8) | 16 (10) | 0.2 |
| HIV transmission risk factor | |||
| MSM | 379 (63) | 38 (24) | |
| IDU | 91 (15) | 100 (63) | |
| Heterosexual | 99 (16) | 17 (11) | |
| Other | 35 (6) | 5 (3) | < 0.001 |
| BMI (kg/m2) | |||
| < 18.5 | 10 (1.7) | 1 (0.6) | |
| 18.5–24.9 | 240 (39.7) | 78 (49) | |
| 25–29.9 | 229 (37.9) | 45 (28) | |
| ≥ 30 | 125 (20.7) | 36 (23) | 0.07 |
| CD4+ cell count current (cells/mm3) | |||
| 0–200 | 103 (17) | 32 (20) | |
| 201–350 | 139 (23) | 46 (29) | |
| >350 | 362 (60) | 82 (51) | 0.1 |
| CD4+ cell count nadir (cells/mm3) | |||
| 0–200 | 327 (54) | 106 (66) | |
| 201–350 | 173 (29) | 34 (21) | |
| >350 | 104 (17) | 20 (13) | 0.02 |
| HIV-1 RNA level peak* (copies/ml) | |||
| ≥100,000 | 209 (35) | 58 (36) | |
| 10,000–99,999 | 196 (32) | 58 (36) | |
| <10,000 | 198 (33) | 44 (28) | 0.4 |
| Currently on ART | |||
| Yes | 423 (70) | 109 (68) | |
| No | 181 (30) | 51 (32) | 0.6 |
| Current illicit drug use (past 3 months) | |||
| Yes | 121 (20) | 68 (42) | |
| No | 483 (80) | 92 (58) | 0.001 |
| Current illicit drug use by drug category | |||
| Cocaine | 68 (11) | 41 (26) | < 0.001 |
| Speed | 71 (12) | 39 (24) | < 0.001 |
| Opiates | 10 (2) | 14 (9) | < 0.001 |
| At-risk alcohol use | |||
| Yes | 104 (17) | 25 (16) | |
| No | 500 (83) | 135 (84) | 0.6 |
| PHQ-9 depression categories | |||
| None (0–4) | 245 (41) | 45 (28) | |
| Mild (5–9) | 166 (27) | 42 (26) | |
| Moderate (10–14) | 95 (16) | 31(19) | |
| Moderately-severe (15–19) | 56 (9) | 26 (16) | |
| Severe (20–27) | 42 (7) | 16 (10) | 0.009 |
*
Missing HIV-1 RNA level data for one patient, therefore N = 763 for this category.
ART: antiretroviral therapy; BMI: body mass index; IDU: injection drug user; MSM: men who have sex with men