Table 2.
Relation between accelerometer-measured active and sedentary behavior and breast cancer
| Measures modeled individually |
Measures modeled simultaneously |
|||||
|---|---|---|---|---|---|---|
| Accelerometer-based measures* |
Cases (n=996) |
Controls (n=1,164) |
Age,BMI& wear time adjusted OR1 (95% CI) |
Multivariable Adjusted OR2 (95% CI) |
Age, BMI & wear time adjusted OR3 (95% CI) |
Age, BMI & wear time adjusted OR4 (95% CI) |
| Overall activity, total counts per day |
||||||
| ≤ 244.79 | 443 | 291 | 1.00 | 1.00 | n/a | n/a |
| 244.80 – 317.72 | 246 | 291 | 0.54 (0.43, 0.68) | 0.52 (0.41, 0.66) | ||
| 317.73-400.62 | 163 | 291 | 0.35 (0.27, 0.45) | 0.33 (0.25, 0.44) | ||
| ≥ 400.63 | 144 | 291 | 0.30 (0.23, 0.39) | 0.29 (0.22, 0.38) | ||
| P-trend | <.0001 | <.0001 | ||||
| Light, min/day | ||||||
| ≤ 225.12 | 384 | 291 | 1.00 | 1.00 | 1.00 | |
| 225.13-265.77 | 272 | 291 | 0.73 (0.58, 0.92) | 0.71 (0.56, 0.90) | n/a | 0.95 (0.72, 1.26) |
| 265.78-305.41 | 189 | 291 | 0.53 (0.41, 0.68) | 0.56 (0.43, 0.72) | 0.88 (0.63, 1.23) | |
| ≥ 305.42 | 151 | 291 | 0.45 (0.34, 0.59) | 0.47 (0.35, 0.63) | 0.87 (0.57, 1.33) | |
| P-trend | <.0001 | <.0001 | 0.23 | |||
| Moderate-to-vigorous, min/day |
||||||
| ≤ 65.0 | 449 | 292 | 1.00 | 1.00 | 1.00 | 1.00 |
| 65.10 - 95.58 | 260 | 290 | 0.56 (0.44, 0.71) | 0.53 (0.41, 0.67) | 0.63 (0.50, 0.81) | 0.59 (0.45, 0.76) |
| 95.59 - 128.24 | 162 | 291 | 0.34 (0.26, 0.44) | 0.32 (0.24, 0.41) | 0.42 (0.31, 0.56) | 0.38 (0.27, 0.51) |
| ≥ 128.25 | 124 | 291 | 0.27 (0.20, 0.35) | 0.26 (0.20, 0.35) | 0.39 (0.27, 0.56) | 0.35 (0.24, 0.52) |
| P-trend | <.0001 | <.0001 | <.0001 | <.0001 | ||
| Sedentary, min/day | ||||||
| ≤ 396.60 | 153 | 291 | 1.00 | 1.00 | 1.00 | 1.00 |
| 396.61-457.74 | 234 | 291 | 1.69 (1.30, 2.21) | 1.64 (1.24, 2.18) | 1.32 (0.99, 1.76) | 1.21 (0.87, 1.68) |
| 457.75-524.10 | 273 | 291 | 2.25 (1.72, 2.94) | 2.13 (1.61, 2.82) | 1.48 (1.08, 2.03) | 1.26 (0.85, 1.88) |
| ≥ 524.11 | 336 | 291 | 3.54 (2.68, 4.68) | 3.45 (2.57, 4.61) | 1.81 (1.26, 2.60) | 1.48 (0.88, 2.49) |
| P-trend | <.0001 | <.0001 | 0.0012 | 0.14 | ||
Overall activity determined by total counts per day averaged across valid days of wear; time spent sedentary or in light and moderate-to-vigorous activity calculated as the average minutes per day across valid days of wear. Categories determined by the quartile distribution among controls; behavior defined by the following counts: sedentary (0-99 counts), overall activity (100+ counts), light (100-759 counts), and moderate-to-vigorous (760+ counts); data for moderate-to-vigorous activity missing for one case.
Age and BMI adjusted models also include adjustment for wear time.
Multivariable models adjusted for the following: age, BMI, education, current smoking status, age at menarche, number of full term births, breast cancer family history, previous screening mammography, history of benign breast disease, menopausal status/age at menopause combination variable, and wear time.
Models include time spent in moderate-to-vigorous and sedentary behavior.
Models include time spent in light, moderate-to-vigorous, and sedentary behavior.