Table 3.

Independent associations of moderate-to-vigorous activity and sedentary time with breast cancer odds, by timing of treatment¹

	Timing of Monitor Wear in Relation to Treatment (No. of cases)
Average minutes per day*	Controls (N=1,164)	Cases	Monitor worn prior to surgery & other treatments (N=141)	Cases	Monitor worn after surgery but prior to other treatments (N=230)	Cases	Monitor worn after surgery & other treatments (N=381)	Cases	Surgery date unknown (N=118)	Cases	Treatment date unknown (N=105)
Moderate-to- vigorous, min/day
≤ 65.0	292	47	1.00	135	1.00	155	1.00	49	1.00	55	1.00
65.10 - 95.58	290	38	0.72 (0.44, 1.17)	50	0.41 (0.27, 0.60)	113	0.83 (0.60, 1.16)	29	0.62 (0.37, 1.06)	24	0.54 (0.31, 0.95)
95.59 - 128.24	291	31	0.56 (0.32, 0.98)	24	0.22 (0.13, 0.37)	70	0.56 (0.37, 0.83)	19	0.44 (0.23, 0.83)	13	0.37 (0.18, 0.77)
≥ 128.25	291	24	0.43 (0.22, 0.86)	21	0.25 (0.13, 0.47)	43	0.42 (0.25, 0.70)	21	0.55 (0.26, 1.17)	13	0.49 (0.21, 1.17)
Sedentary, min/day
≤ 396.60	291	24	1.00	24	1.00	63	1.00	24	1.00	15	1.00
396.61 - 457.74	291	41	1.37 (0.78, 2.42)	50	1.52 (0.86, 2.68)	86	1.22 (0.82, 1.84)	26	1.07 (0.56, 2.02)	21	1.38 (0.64, 2.94)
457.75 - 524.10	291	43	1.30 (0.70, 2.39)	65	1.85 (1.02, 3.34)	96	1.36 (0.88, 2.12)	35	1.41 (0.72, 2.75)	31	1.95 (0.88, 4.31)
≥ 524.11	291	33	0.78 (0.37, 1.63)	91	2.40 (1.26, 4.57)	136	2.25 (1.37, 3.70)	33	1.37 (0.63, 3.00)	38	2.52 (1.05, 6.07)

^*Time spent sedentary or in moderate-to-vigorous activity calculated as the average minutes per day across valid days of wear. Categories determined by the quartile distribution among controls; behavior defined by the following counts: sedentary (0-99 counts) and moderate-to-vigorous (760+ counts); data for moderate-to-vigorous activity missing for one case.

¹Models adjusted for the following: age, BMI, and wear time. Cases who wore the monitor prior to surgery and after other treatments were excluded from these analyses (n=21) due to small numbers across accelerometer categories.