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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Hypertension. 2012 Sep 4;60(4):1023–1030. doi: 10.1161/HYPERTENSIONAHA.112.196576

Figure 1.

Figure 1

Augmented pressor effects induced by AngII during the expression (E) period in rats after peripheral (Fig 1A) or central (Fig 1B) treatment with a subpressor dose of Aldo during the induction (I) period. This effect was attenuated by central blockade of MR. Figures 1C and 1D show the changes in MAP and HR after infusion of AngII during E in all groups. I-S = peripheral treatment with saline during I; I-Aldo = peripheral treatment with Aldo during I; I-Aldo/icv RU = peripheral treatment with Aldo plus central treatment with RU28318 (RU) during I; I-icv S = central treatment with saline during I; I-icv Aldo = central treatment with Aldo during I; E-S = peripheral treatment with saline during E; E-AngII = peripheral treatment with a pressor dose of AngII during E. (* p<0.05 vs. baseline or I–Aldo+E-S, # p<0.05 vs. I-S+E-AngII, I-icv S+E-AngII or I-Aldo/icv RU+E-AngII).