Figure 1.
Promoter methylation status of the previously identified DNA methylation markers in normal and tumor tissue samples. The figure illustrates the methylation status of the previously identified DNA methylation biomarkers across test and validation sets of colorectal carcinomas (n=169), adenomas (n=104), normal mucosa samples from colorectal cancer (CRC)-free individuals (n=107), and normal mucosa from CRC patients (n=105). For comparison the methylation status of the novel epi-panel for early detection of CRC is included.11 Green color indicates unmethylated sample, whereas red color indicates methylated sample.