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. 2012 Oct 2;15(1):15–29. doi: 10.1208/s12248-012-9409-7

Fig. 1.

Fig. 1

Schematic representation of the PK/PD model. The dotted lines and bars depict stimulatory (open bar, represents increase in T in) and inhibitory (closed bar) effects of pramlintide on the various processes via indirect mechanisms. Symbols are defined in Tables I–III