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a In vitro precipitation profiles of two formulations containing NVS562 in FaSSIF or FeSSIF media. Observed plasma concentrations are shown in solid circles (black fasted, gray fed) and simulated PK profile are presented as solid curves (black fasted, gray fed) after a single administration of 150 mg of NVS562 given as a b SEDDS or c tablet in healthy volunteers. d Parameter sensitivity of precipitation time to the change of fraction absorbed
