Table 5.
Region | BA | x | y | z | T | Z | p value |
---|---|---|---|---|---|---|---|
Right parahippocampus | 29 | −36 | −8 | 8.6 | 7.69 | <0.001 | |
Right hippocampus | 26 | −10 | −15 | 8.1 | 7.32 | <0.001 | |
Right insula | 13 | 40 | −3 | 12 | 8.77 | 7.8 | <0.001 |
Right middle cingulate/precuneus | 31 | 5 | −54 | 26 | 7.61 | 6.94 | <0.001 |
7 | −49 | 32 | 7.38 | 6.77 | <0.001 | ||
Right orbital frontal | 11 | 23 | 30 | −17 | 5.95 | 5.61 | <0.001 |
28 | 37 | −13 | 5.53 | 5.24 | 0.002 | ||
Left hippocampus/parahippocampus | −26 | −39 | −8 | 5.55 | 5.27 | 0.002 | |
Left hippocampus | −22 | −12 | −23 | 5.75 | 5.44 | 0.001 | |
Left insula/middle temporal gyrus | 13 & 21 | −39 | 0 | 7 | 7.54 | 6.89 | <0.001 |
−37 | 9 | 5 | 7.05 | 6.51 | <0.001 | ||
−54 | −26 | −6 | 6.31 | 5.9 | <0.001 | ||
Left superior middle frontal | 11 | −6 | 38 | 27 | 7.21 | 6.63 | <0.001 |
−7 | 41 | −4 | 7.09 | 6.54 | <0.001 | ||
Left middle cingulate/precuneus | 31 | −1 | −38 | 34 | 7.76 | 7.06 | <0.001 |
Left anterior cingulate | 10 & 32 | −7 | 45 | 15 | 8.33 | 7.49 | <0.001 |
Left middle frontal | 10 | −27 | 48 | 26 | 5.65 | 5.36 | 0.001 |
Left frontal | 10 | −25 | 57 | 5 | 5.95 | 5.61 | <0.001 |
Adjusted for age, gender, APOE-ε4 carrier status, g′, and f. Higher d scores are associated with greater gray matter volume in these regions. Family-wise error corrected, minimum cluster size k = 50. Bonferonni corrected to p < 0.003.