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. Author manuscript; available in PMC: 2013 Nov 27.
Published in final edited form as: Biochemistry. 2012 Nov 13;51(47):9581–9591. doi: 10.1021/bi301132k

Figure 6.

Figure 6

Folding free energies of the dimer vs. the trimer computed from parallel tempering simulations at various temperatures. For these computations, conformations were collected every 5 ns (total of 180 conformations at each temperature). The folded state was defined based on Cα rmsd from the crystal structure. Uncertainties are computed as described in Methods.