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Percentage of Ca2+ current blocked by different blockers at 0 mV step voltage
| L type | P/Q type | N type | R type | Total | |
|---|---|---|---|---|---|
| Blocker | Nimodipine | ATX | CTX | rSNX-482 | |
| Concentration | 10 μm | 1 μm | 1 μm | 200 nm | |
| Apex | 41.0 ± 4.5% | 17.2 ± 2.7% | 22.6 ± 4.3% | 15.9 ± 5.7% | 81.6 ± 7.8% |
| Base | 31.2 ± 2.9%* | 11.5 ± 5.9% | 12.6 ± 2.3%* | 19.5 ± 5.1% | 71.1 ± 6.2% |
*p < 0.05 (apex vs base) (n = 6).
