Table 3.
Comparison of previous reports on Ca2+ currents/channels in SGNs
| Reference | Preparation | Current/s | Sensitivity | α-Subunit | Methods | Predicted functions |
|---|---|---|---|---|---|---|
| Lv et al. (this paper) | Posthearing murine SGNs | L, N, P/Q, RT types | Cd2+, DHPs, CTX, ATX, rSNX482, mibefradil | Cav1.3, Cav2.1–3, Cav3.1–3 | EP, IC, WCVC, SC/IM | Spike latency, amplitude, width, AHP spike frequency, pattern activation of outward currents |
| Chen et al., 2011 | Prehearing murine SGNs | N/A | Cd2+ | Cav1.3, Cav2.2, Cav3.3 | EP, IC/IM | |
| Lopez et al., 2003 | Posthearing chinchilla SGNs | N/A | N/A | IM | Spike shape of APs | |
| Jimenez et al., 1997 | Embryonic day 6–17 chicks | L, N types | Cd2+, DHPs, ω-conotoxin GVIA | N/A | EP, WCVC | Neuronal development |
| Hisashi et al., 1995 | Posthearing guinea pig SGNs | L type | La3+, Cd2+, Ni2+, Co2+, DHPs | N/A | EP, WCVC | Spike shape of APs |
EP, electrophysiology; IC, current clamp; WCVC, whole-cell voltage clamp; SC, single-channel recordings; IM, immunolocalization; AP, action potential.