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a Structure of human neuroglobin (Ngb) with the Cys46-Cys55 disulfide bridge formed obtained by molecular dynamics simulations [27]. The prosthetic group (heme), the two distal (His64) and proximal (His96) histidines, and the two cysteines (Cys46 and Cys55), located on the CD loop, are represented as licorice (VMD drawing method). b Structure of the heme molecule. The carbon atoms are numbered according to the Fischer numeration and the α–γ meso axis is shown as a dashed line
