Table 5.
Substrates shown here have not been further biochemically validated. Sequences are given in the one letter code. Arrows indicate the cleavage sites analyzed by MS/MS for meprin α (α) and meprin β (β). Numbers display position of amino acids in full-length proteins. Confirmed cleavage sites in the protein and identified in more than one secretome (biological replicate) are indicated in bold.
HSP heat-shock protein, HLA-A HLA class I histocompatibility antigen, CD99 cluster of differentiation, SMOC2 SPARC-related modular calcium-binding protein 2, SPARC secreted protein acidic and rich in cysteine, LTBP latent-transforming growth factor β-binding protein.