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Compaction of 3D hydrogels by mitral valve interstitial cells (MVIC) from normal valves and valves with mild myxomatous degeneration. Gels of each cell source were cultured with or without TGFß1. Compaction was quantified as projected area with respect to original (Day 0) area. A significant compaction amongst the groups was noted at day 7 with the pairwise comparisons revealing a significant difference only between the treated and nontreated myxomatous cell hydrogels
