Table 1.
Risk factors and outcomes of MPI
| Variable | Major infection (n = 341) | No major infection (n = 10,181) | Unadjusted OR (95% CI) | P value | aOR (95% CI) | P value |
|---|---|---|---|---|---|---|
| Risk factors | ||||||
| Caucasian | 278 (81.5) | 8,930 (87.7) | 0.6 (0.5–0.8) | .0007 | 0.73 (0.54–0.97) | .03 |
| BMI, kg/m2* | ||||||
| ≥30 and <40 | 120 (35.2) | 3,267 (32.1) | 1.3 (1.0–1.6) | 1.31 (1.03–1.66) | .028 | |
| ≥40 | 32 (9.4) | 437 (4.3) | 2.5 (1.7–3.7) | 2.48 (1.66–3.71) | <.0001 | |
| Emergent surgery | 15 (4.4) | 210 (2.1) | 2.2 (1.3–3.7) | .0034 | 1.99 (1.13–3.48) | .017 |
| Diabetes | 154 (45.2) | 3,481 (34.2) | 1.6 (1.3–2.0) | <.0001 | 1.25 (1.00–1.58) | .063 |
| Renal failure | 54 (15.8) | 550 (5.4) | 3.3 (2.4–4.5) | <.0001 | 2.25 (1.54–3.28) | <.0001 |
| Chronic lung disease | 0.73 (0.55–0.97) | .029 | ||||
| Cerebrovascular accident | 49 (14.4) | 807 (7.9) | 2.0 (1.4–2.7) | <.0001 | 1.57 (1.14–2.17) | .006 |
| Peripheral vascular disease | 88 (25.8) | 1,640 (16.1) | 1.8 (1.4–2.3) | <.0001 | 1.47 (1.13–1.92) | .004 |
| Immunosuppressive treatment | 22 (6.5) | 284 (2.8) | 2.4 (1.5–3.8) | <.0001 | 1.97 (1.23–3.13) | .005 |
| Previous CABG | 41 (12.0) | 747 (7.3) | 1.7 (1.2–2.4) | .0012 | 1.72 (1.22–2.43) | .002 |
| Congestive heart failure | 108 (31.7) | 2,094 (20.6) | 1.8 (1.4–2.3) | <.0001 | 1.30 (1.01–1.67) | .043 |
| NYHA class IV | 121 (35.5) | 2,702 (26.5) | 1.5 (1.2–1.9) | .0002 | 1.38 (1.09–1.74) | .007 |
| Outcomes | ||||||
| 30-day mortality, n (%) | 29 (8.5) | 227 (2.2) | <.0001 | |||
| Postoperative LOS, days, median | 15.0 | 6.0 | <.0001 | |||
CABG, coronary artery bypass graft surgery; NYHA, New York Heart Association.
*
Reference group was BMI <30 kg/m2.