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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: J Comput Aided Mol Des. 2012 Nov 21;26(12):1343–1353. doi: 10.1007/s10822-012-9618-2

Fig. 4.

Fig. 4

UPGMA tree generated with MEGA5. Parameters: complete deletion, Dayhoff model, uniform rates of substitution. Tested with Bootstrap n = 1,000. Double mutant P. falciparum (C59R, S108N) and quadruple mutant P. falciparum (N51I, C59R, S108N, I164L) are also shown relative to the wt P. falciparum