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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: J Immunol. 2012 Dec 3;190(1):307–316. doi: 10.4049/jimmunol.1201644

Figure 6. Poly IC:LC (Hiltonol™) treatment improves survival of mice infected with S. pneumoniae.

Figure 6

WT (A) or IRAK4KDKI (B) mice were infected i.n. with 1 × 105 S. pneumoniae in a total volume of 50 μl of Poly IC:LC (100 μg/mouse, open circle) or saline (vehicle, open square). Survival was assessed over the course of 14 days. The data represent the combined data of 3 separate experiments with a total of 11 mice per group (10 mice for WT vehicle group). (*) indicates log-rank test, p = 0.0097; (**) indicates log-rank test, p = 0.0001.