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α5 integrin, compared to α2 integrin, appears more greatly increased and localized to endothelial cells in human BAVM compared to control (epilepsy) tissue. Co-immunohistochemistry of CD31 (Abcam) with A. α5 (Millipore) or B. α2 (Chemicon International). Original magnification × 200. Note that the increased α2 in BAVM displays a more diffuse staining pattern than α5 in BAVM.
