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. 2012 Dec 22;9(1):78–93. doi: 10.7150/ijbs.5626

Figure 4.

Figure 4

Differentiation of grafted GRPs after SCI. (A) Grafted GRPs survived and migrated in the white matter and sent multiple processes longitudinally. (B) The grafted GRPs differentiated into oligodendrocyte like cells with multiple processes. (C) The processes of oligodendrocyte like grafted GRPs formed close relationship with the host axons. (D-F) The grafted GRPs differentiated into oligodendrocytes expressing oligodendrocyte specific marker APC (arrows). (G-I) Many grafted GRPs also differentiated into GFAP positive astrocytes. Scare bars: 20 µm.