Table 2.

Effect of Gender on EOMG Associations

gendera	locus	marker	ORb	OR 95% CI	p-value	gender pc
Female	PTPN22	rs2476601	1.72	1.42 – 2.10	6.02E-08	0.93
Male			1.71	1.16 – 2.51	6.46E-03
Female	TNIP1	rs4958881	1.73	1.42 – 2.12	6.77E-08	0.76
Male			1.80	1.23 – 2.62	2.50E-03
Female	MHC	HLA_B*08	6.92	4.28 – 5.91	8.48E-96	<0.0001
Male			3.55	2.46 – 4.56	1.89E-13

^aThe number of female cases was 538 and the number of male cases was 111. The female and male analyses were matched 3:1 and 8:1with controls, respectively. All analyses were controlled for population substructure as in the main analyses.

^bOR, odds ratio.

^cThe p-valuefor gender difference was calculated using an unpaired T test.