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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Genesis. 2012 Sep 12;50(12):908–913. doi: 10.1002/dvg.22052

Figure 3. In-vivo Cre activation.

Figure 3

The indicated mice were treated in-vivo with tamoxifen (See Methods). EYFP expression was analyzed as a measure of Cre activation and representative FACS plots of the indicated parameters are shown. In (a) histogram plots show EYFP expression in un-gated live cells from the spleen of the indicated mice. Tow parameter contour plots show CD4 versus CD8 expression in gated YFP+ and YFP− cells as shown by the arrows. (b) Line histograms show EYFP expression in cells harvested from the spleen of the indicated mice and gated for surface expression of the indicated markers. Data are representative of three independent experiments.