Table 1.
Influenza A(H3N2) properties
| Amino acid position |
Hemagglutination titer* |
Virus plaquing efficiency |
||||||||||
| Virus | 190 | 193 | 222 | 225 | 226 | 227 | Chicken | Turkey | Guinea pig | SIAT | MDCK | Ratio |
| X31 (A/Aichi/2/68) | E | S | W | G | L | S | 2,048 | 4,096 | 1,024 | 2 × 107 | 1 × 107 | 2 |
| A/Toulouse/878/2001 | D | S | W | G | V | S | 4 | 512 | 256 | 3 × 106 | 3 × 106 | 1 |
| A/Trieste/2/2003 | D | S | R | D | V | S | < | 16 | 128 | 1 × 104 | 1 × 103 | 10 |
| A/Finland/486/2004 | D | S | R | D | I | P | < | 512 | 8,192 | 4 × 103 | 2 × 102 | 20 |
| RG/Finland/486/2004 S193F | D | F | R | D | I | P | < | 128 | 1,024 | 8 × 106 | 4 × 105 | 20 |
| RG/Finland/486/2004 D225N | D | S | R | N | I | P | < | < | 512 | 3 × 104 | 4 × 102 | 75 |
| A/Hong Kong/4443/2005 | D | F | R | N | I | P | < | < | 32 | 4 × 104 | 1 × 103 | 40 |
| A/Esfahan/6117/2010 | D | F | R | N | I | P | < | < | 64 | 2 × 104 | 5 × 101 | 400 |
| A/Hong Kong/3615/2010 | D | F | R | N | I | P | < | < | 64 | 2 × 104 | 1 × 101 | 2,000 |
The table shows sequence variation in the vicinity of the receptor binding site of the HA, HA titer with RBCs of different species, and the relative plaque formation on MDCK cells and MDCK-SIAT1 cells.
*The symbol “<” indicates no agglutination of RBCs was observed.