Table 1.
cell type (antibody) | intratumoral | peritumoral | |||||
cells / mm2 | % of patients | cells / mm2 | % of patients | ||||
eosinophils | (EG-2) | n = 159 | n = 140 | ||||
none/few | 0-10 | 29 | 0-50 | 31 | |||
moderate | 11-50 | 50 | 51 - 200 | 43 | |||
many | > 50 | 21 | > 200 | 26 | |||
neutrophils | (elastase) | n = 160 | n = 152 | ||||
none/few | 0-5 | 21 | 0 - 75 | 24 | |||
moderate | 6 - 50 | 54 | |||||
many | > 50 | 25 | > 75 | 76 | |||
mast cells | (tryptase) | n= 160 | n = 151 | ||||
none/few | 0 -5 | 19 | 0-30 | 25 | |||
moderate | 6 -50 | 52 | 31 -100 | 59 | |||
many | > 50 | 29 | > 100 | 16 | |||
macrophages | (CD68) | n = 159 | |||||
none/few | 0-50 | 28 | |||||
moderate | 51 -150 | 50 | |||||
many | > 150 | 22 | |||||
NK cells | (CD56) | n = 159 | n = 136 | ||||
none | 0 | 33 | 0 | 43 | |||
moderate/many | > 0 | 67 | > 0 | 57 | |||
T cells | (CD3) | n = 158 | n = 157 | ||||
none/few | 0-55 | 27 | 0-300 | 20 | |||
moderate | 56-105 | 36 | 301 - 500 | 51 | |||
many | >105 | 37 | > 500 | 29 | |||
CD4+ cells | n = 156 | n = 130 | |||||
none/few | 0-30 | 43 | 0-20 | 24 | |||
moderate | 31 -65 | 26 | 21 -110 | 50 | |||
many | >65 | 31 | > 110 | 26 | |||
CD8+ cells | n = 159 | n = 122 | |||||
none/few | 0-15 | 26 | 0-135 | 77 | |||
moderate | 16-75 | 47 | |||||
many | >75 | 27 | > 135 | 23 |
Peritumoral infiltrate could not be reliably determined in all patients, because of the absence of invasive front in several tumor samples.