Architecture of the CF I complex. (A) The CF I complex composed of Rna14, Rna15, Hrp1 and RNA is shown to have an inverted U-like structure where Rna14 provides the base of inverted U, whereas Hrp1 and Rna15 form the end arms. (B) The top view of CF I complex provides a different impression of the shape of the complex. The two RRMs of Hrp1 (colored in magenta) form the two corners of the triangle, whereas Rna14 (colored in olive) forms the third corner. (C) Surface view of the Hrp1 and Rna14 interface. Hrp1 is shown in magenta, whereas Rna14 is in olive. Residues N201 to Q240 of Rna14 are shown in a surface representation. (D) The interactions between loop 3 of Hrp1 and loop 5 of Rna15 are highlighted; the distance between Thr196 (Cγ2) of Hrp1 and Asp98 (Cγ) of Rna15 is shown explicitly.