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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Exp Mol Pathol. 2012 Sep 23;94(1):255–261. doi: 10.1016/j.yexmp.2012.09.009

Figure 3. Rapamycin down regulates HIV gene expression in vivo and in vitro.

Figure 3

A. Total RNA was extracted from Tg26 mice and Rapa-receiving Tg26 mice (n=4). Real time PCR studies were carried out to quantify HIV gene expression (n=4). *P<0.0.1 compared with respective Tg26. **P<0.001 compared with respective Tg26.

B. Total RNA were extracted from HIV/CIDHPs and HIV/CIDHPs/Rapa and probed for HIV genes (n=4). HIV/CIDHP/Rapa displayed attenuated expression of Nef, gp160, Tat, and Vpr when compared to HIV/CIDHPs.