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Statistical comparisons of the pharmacokinetics of S/GSK1265744 alone or in combination with etravirine
| PK parametera | Plasma S/GSK1265744 + ETR vs S/GSK1265744 (GLS mean ratio [90% CI])b |
|---|---|
| AUC0-τ | 1.01 (0.956–1.06) |
| Cmax | 1.04 (0.987–1.09) |
| C0 | 0.854 (0.792–0.921) |
| Cτ | 0.999 (0.942–1.06) |
C0, drug concentration at the beginning of the dosing interval before administration of study drug for purposes of PK assessment (n = 12).
GLS, geometric least squares.
