Table 1.

Origin, in vitro susceptibilities, and underlying azole resistance mechanisms of VCZ^s and VCZ^r A. fumigatus isolates

A. fumigatus isolatea	Cyp51A substitution	MIC (mg/liter)			Anidulafungin MEC (mg/liter)
		Amphotericin B	Posaconazole	Voriconazole
AZN 8196	None	0.5	0.031	0.25b	0.031
V52-35	TR34/L98H	0.5	0.5	4c	0.031

^aThe A. fumigatus isolates were from patients with proven invasive aspergillosis.

^bSusceptible.

^cResistant.