Table 3.

Time-kill assay

Peptide	Changes in CFU valuesa (Δlog) for strain and MIC strength and conclusion
	E. coli BL21 AI		E. coli DSM 10233		K. pneumoniae DSM 681
	10× MIC	1× MIC	10× MIC	1× MIC	10× MIC	1× MIC
Control	2.9 (2.0)	2.4 (0.1)	1.8	2.9	2.1	1.4
Api88	< −3 (−2.3), bactericidal	< −3 (−2.2), bactericidal	< −3, bactericidal	< −3, bactericidal	< −3, bactericidal	−3, bactericidal
Api137	<-3 (−2.1), bactericidal	2.4 (−2.9), bacteriostatic	< −3, bactericidal	< −3, bactericidal	−3, bactericidal	∼1, bacteriostatic
Api155	< −3 (−2.8), bactericidal	0.8 (−2.6), bacteriostatic	< −3, bactericidal	< −3, bactericidal	∼1, bacteriostatic	∼1, bacteriostatic

^aCFU count after an incubation time of 24 h (6 h).