Table 4.
Antimicrobial activities of Api137 and Api137 (R4A) against clinically relevant Gram-negative pathogensa
| Pathogen | No. of tested strains and isolates | MIC (μg/ml) range |
|
|---|---|---|---|
| Api137 | Api137 (R4A) | ||
| E. coli | 8 | 0.5 | 0.25–0.5 |
| K. pneumoniae | 6 | 0.25–0.5 | 0.25–1 |
| P. aeruginosa | 8 | 2–8 | 4–16 |
| A. baumannii | 5 | 1–2 | 0.5–1 |
| E. cloacae | 5 | 0.25 | 0.25–0.5 |
| P. vulgaris | 5 | 0.125–2 | 0.25–4 |
For further details, see Table S2 in the supplemental material.