Fig 2.

Kaplan-Meyer curves in rats during the course of left-sided pneumonia caused by the WT K. pneumoniae strain (A) or the ESBL-positive K. pneumoniae strain (B). Rats (12 per group) were treated with tigecycline starting 24 h after bacterial inoculation of the left lung. Tigecycline was administered intraperitoneally every 12 h with doses of 6.25 (▼), 12.5 (●), or 25 (■) mg/kg for 10 days. Untreated rats (⧫) are also shown. Rat survival rates were monitored daily until 10 days posttreatment.